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August 22, 2005

The cold, hard facts on cryonics? Or cold-hearted journalism?

Front page news from today's Chicago Tribune. -- It's unfavorable reviews like this that give transhumanist goals a bad rap. What can we do to counter the negative press?

The cold, hard facts on cryonics
Progress aside, don't hold your breath for immortality

By Howard Witt
Tribune senior correspondent
Published August 22, 2005


SCOTTSDALE, Ariz. -- Such is the breathtaking pace of modern scientific advancement that in the three short years since the technicians at the Alcor Life Extension Foundation famously severed baseball star Ted Williams' head from his torso and deep-froze the parts for anticipated resurrection at some future date, there have been a number of improvements to the preservation process.

Antifreeze much better than anything in your car is now pumped into a client's corpse. State-of-the-art cooling techniques are used to chill the body parts down to minus 320 degrees Fahrenheit before they are stored inside tall stainless steel tanks that look like they might have come from a microbrewery. The battered bicycle helmet that used to be strapped onto the deceased's head during the cooling phase is soon to be replaced with something more clinical-looking.

But the experts here, who have been struggling to perfect their techniques since 1972, still haven't quite conquered the ultimate bane of cryonics practitioners everywhere: the unfortunate phenomena known in the trade as "acoustic fracturing events."

In layman's terms, those would be the audible cracking noises made by the brain and other internal organs as they shatter from the effects of the extreme cold.

"It's exactly that kind of noise when you drop an ice cube into a glass of Coke," explained Tanya Jones, Alcor's director of technical operations. "In the best-case scenario we've ever had, it was only five fracture events. We are working on the engineering to see how to eliminate this problem."

And what will happen to all those fractured organs if the bodies can someday be thawed out and revivified?

"It should just be a matter of stitching them back together," Jones said. "You might be able to glue them together, but we don't have repair technologies on that scale yet."

Achieving immortality, it turns out, is not going to be easy. But that's no discouragement to the true believers in cryonics, the study of freezing freshly deceased bodies so that they might one day be revived and treated for whatever caused them to perish.

There are now at least five cryonics facilities in the United States, of which Alcor claims to be the largest. The oldest one, the American Cryonics Society ("Freezing people for more than three decades") was founded in 1969 in Cupertino, Calif. The newest company, Suspended Animation, recently received zoning permission to open a facility in Boynton Beach, Fla., which puts it at the heart of a burgeoning retiree market that presumably has the most urgent need of such services.

`It's a crapshoot'

Mainstream biologists may scoff at cryonics, rating the successful reanimation of a frozen human being about as likely as re-creating a cow from a pound of frozen ground beef. And even the most devout cryonicists acknowledge that no technologies currently exist to realize their resurrection dreams.

But the critics, they point out, will be long dead a few centuries from now. And the flash-frozen expect to have the last laugh.

"It's all iffy, but if I don't try it, for sure I won't be reanimated," said Dr. David Hall, a retired psychiatrist in Pasadena, Calif., who has arranged to join the 68 other frozen clients currently padlocked inside Alcor's vats when he dies. "It's a crapshoot. But you know, it might work."

Cryonics is very much a "now and later" science, requiring of its adherents a lot of cash now--Alcor charges $150,000 to preserve a whole body, $80,000 for just the head--and a lot of faith later that what seems like science fiction will someday become fact.

"As far as the unproven aspect of the technology, cryonics is no different than the folks who are trying to find a cure for cancer," said Joseph Waynick, Alcor's CEO and president. "There's no cure for lung cancer, for example. Yet we spend hundreds of millions of dollars a year searching for one. It's no more speculative than that, or any other advanced medical procedure that's experimental right now."

Alcor says it has 765 members who have paid their fees, many by purchasing life insurance policies for the purpose. New customers are generated through referrals and events such as Cryofeast 2005, a potluck picnic scheduled for later this month in Sunnyvale, Calif. ("Fridge available," the invitation notes.)

Processing a `patient'

Members who die become "patients" in the Alcor vocabulary, and what happens next is not for the squeamish.

Ideally, a volunteer Alcor paramedic team will be able to rush to the hospital or hospice and begin cardiopulmonary resuscitation to keep blood flowing to the brain and internal organs while a preservation solution is pumped into the veins.

Those who can't be reached immediately and are shipped off to funeral homes face inevitable ischemia as their organs rapidly decompose from lack of oxygen. Alcor will still freeze them, but their future prospects are not considered as bright. And if the funeral home has already embalmed a patient with formaldehyde, or the patient has been autopsied or committed suicide with a gunshot to the head, they are really in trouble.

The patient is next packed in ice and transported to Alcor's Scottsdale facility, which is in a nondescript office park next to an interior design company. There, in a makeshift operating room, the blood is drained from the patient's body and replaced with a special glycerol antifreeze.

If the patient has opted for preservation of just the head--the assumption being that future scientists will be able to grow a new body for it or else extract the personality and memories from the brain--it is detached from the body and placed in a special plexiglass box. In either case, holes are drilled into the skull to observe the brain and make sure the antifreeze is infusing evenly, and then the holes are plugged with wax.

Finally, the patient is frozen in nitrogen gas and lowered with a crane into one of the large storage vats, which can each hold up to 10 whole clients alongside several heads.

There's also a vat for pets of members, and it now contains about two dozen cats and dogs.

"Oddly enough, the pets can have better preservation right now than humans," said Alcor's Jones, "because a veterinarian can come in and euthanize them, so at the time of death we can be all prepared, no surprises."

Attractive to celebrities

There's no telling whether any given Alcor patient will end up bumping elbows with Williams, Alcor's most famous client, whose head and torso are stored separately here. Alcor officials do not like to talk much about the baseball legend, whose interment in 2002 after a protracted family squabble over his last wishes landed the company in the headlines.

The only other near-celebrity who has been publicly identified as an Alcor member is Charlie Matthau, son of Walter Matthau. The late actor resisted his son's entreaties to join. Alcor also boasts bona fide scientists and physicians such as Hall among its members, which company officials believe further boosts the legitimacy of their efforts.

But ask credentialed cryobiologists--scientists who specialize in the behavior of organisms at low temperatures--what they think of cryonics and they universally cringe. They fear that their little-understood field, which seeks better ways to temporarily preserve organs for transplant or buy time for critically injured soldiers on a battlefield by slowing their metabolism so they can be transported to a field hospital, has been hopelessly confused with cryonics.

"What they are pursuing is not science, and they are banned from membership in our bylaws," said John Bischof, a professor of mechanical engineering at the University of Minnesota and an official of the Society for Cryobiology. "There's absolutely not one shred of evidence that they will ever be able to reanimate these people. The science doesn't exist."


Posted by Upwinger at August 22, 2005 05:43 PM
Comments

I have to take issue with this article. Cryonics is the second worst things that can happen to you. If given two choices and only two choices - becoming worm food, or a corpsicle with a small possibility of re-animation, which choice are you going to make? At least with cryonics there is some chance. Damage from freezing is a hell of lot better than worm food! Poo poo it all you want, but until there is a better alternative to death, other than cryonics, cryonics is all we have. In the meantime progress towards extending life indefinitely continues a pace, with organ and cellular regenerative medicine right around the corner and nanotechnology not far behind that.

Posted by: Paul Hughes at August 22, 2005 09:18 PM

I hope me posting this article isn't taken as me condoning the attitude of the original author. While his review could've been worse, it wasn't exactly favorable, or even fair. I was just surprised to see cryonics featured on the front page of today's Tribune, and thought I'd share the "news," hoping that maybe someone else could come to Alcor's defense better than I am capable, and maybe contact the original author, if anything he wrote was a distortion or misconception of the facts.

While I currently have no $$ to put towards my own preservation, Ettinger is one of my heroes, and a truer transhumanist than most. Again, I didn't post this because I share the original author's sentiments, but hoping that in countering some of his pessimism, a better argument in favor of cryonics could be restated.

Upwinger

Posted by: Upwinger at August 22, 2005 10:12 PM

I suppose it was the title that put me on the defensive, not anything you did specifically. Frankly, our cause is marginal enough as it is, that I do my best to provide pro-active future-positive information on this site, and not the jaded, shrill and cynical bullshit that passes for journalism these days. His chosen title alone gives his opionion, and the so-called 'facts' are given with a definite anti-cryonics bias throughout. The quote at the end about how cryonics is not science is totally bullshit. Maybe its not his kind of science, but it is still science in the truest sense of the word. Cryonics and cryobiology applied to freezing human tissue with the minimal amount of damage. What is NOT scientific about that? Becuase he happens to think that this particular application goes against his "morals" or it "grosses him out". Rediculous. Worse, because of the articles utterly predicatable bias, that many more people who could be turned on to the hope of immortality have been turned away, except for the already savvy reader.

Posted by: Paul at August 22, 2005 10:57 PM

No one mentioned the possible role of nanotechnology in repairing the internal organs. Instead reference is made to some kind of 'glue?' :O

What really puzzles me is why this story was front page news all of a sudden. It smells of 'moral indignation.' --- The question stands, and is open to all, how can we effectively and proactively counter such unfavorable press?

Posted by: Upwinger at August 23, 2005 05:49 AM

Well, it really didnt seem unfavorable. It seemed like the classic take both sides strategy of a lot of reporting. But what was most fascinating to me are these "acoustic fracturing events". It makes me visualize these planes in the brain that are offshifted from the other side, but are otherwise fully intact. I have no doubt that they can be repaired in the future. And i also have no doubt that the personality can be re-invoked somehow based on the brain patterns. But a situation where... you basically "wake up" again after being in a hospital 50 years ago, I'm not entirely sure if that's possible, but perhaps it is. We may decide that it's de-evolution or trivial to re-animate these "old minds" in a post-eschaton world.


Posted by: liquis at August 23, 2005 06:07 AM

I think it trys to come off as 'balanced', but the end result of this article is that cryonics if for kooks. As for your question upwinger, the cryonics community at large does what it can to promote a positive image with some success. For example, in Arizona last year they tried to outlaw it, but the cryonics community banded together and had the bill killed. Ultimately I think it doesn't really matter how much bad press it gets, as long as they allows "us kooks" to continue having free choice in what happens to us if we die. As long as cryonics and more importantly pro-longevity therapies are legal we are in good shape. Alreadyt the tide in congress is shifting away from Bush's anti-stem-cell stance. Bill Frist stand for stem-cell research was a huge turning point in my opinion.

Posted by: Paul at August 23, 2005 07:53 AM

I urge everyone to read Alcor's FAQs at http://www.alcor.org/FAQs/index.html on the cryonics process. A couple of months ago, I did and I was in for a disappointment. Sad to say, the artice isn't far off the mark. Alcor themselves clearly state that the freezing process does lead to irreparable cell damage. to quote from their FAQ:

Q: Why isn't vitrification reversible now?

A: To vitrify an organ as large as the brain, Alcor must expose tissue to higher concentrations of cryoprotectant for longer periods of time than are used in conventional organ and tissue banking research. The result of this exposure is biochemical toxicity that prevents spontaneous recovery of cell function. In essence, Alcor is trading cell viability in exchange for the excellent structural preservation achievable with vitrification.

and these are the true believers speaking.

Cryonics may be viable one day, but as things now stand, entropy still has the upper hand.

Posted by: Alex at August 23, 2005 09:52 AM

Possible alternative to cryonics: In a speech about aging titled, Why dramatic life extension matters now, at Stanford Univ. on June 8 of this year, Aubrey de Grey stated that an option was to do a brian scan with high enough resolution (I don't think this is anywhere close to being available today, is it?) You would have scans every so often to keep up to date. Then at a later date, when the technology allowed, you'd be able to re-animate your brain state, although not necessarily biologically. Problem is, adequate high res brain scans might be far off.

Posted by: Stan at August 23, 2005 10:06 PM

Forgot to mention, you can check out audio of the speech here: http://www.stanford.edu/group/transhumanism/materials.htm
see bottom of the page.

Posted by: Stan at August 23, 2005 10:07 PM

I agree with Paul that *if* it came down to a choice between death and cryonics--I'd choose cryonics--but the details of it still seem sketchy to me. It still seems a gamble--because who knows if your brain will be able to be revived.

Even Tim Leary decided not to take the cryonics option, after agreeing to it for a while before his death. It was reported that it was mainly a disagreement with that particular cryonics firm..but maybe there were other issues as well.

Posted by: Sly Stoner at August 27, 2005 01:51 AM

Veri nice site!

Posted by: Barbie at September 2, 2005 10:26 AM

If you have your head cut off is it possible to revive you in the future, and is this considered time travel

Posted by: shnark at September 3, 2005 06:59 PM

I heard from a very reliable source that cyrogenics can be used to send people to the future

Posted by: SHNARK at September 3, 2005 07:01 PM

i heard from a very reliable source that the person above is an idiot

Posted by: Idiot Finder at September 3, 2005 07:02 PM